SYLLABUS
PHARMACOLOGY
1. General Pharmacology
- Introduction and scope of Pharmacology
- Various routes of drug administration - advantages and disadvantages
- Drug absorption - definition, types, factors affecting drug absorption
- Bioavailability and the factors affecting bioavailability
- Drug distribution - definition, factors affecting drug distribution
- Biotransformation of drugs - Definition, types of biotransformation reactions, factors influencing drug metabolisms
- Excretion of drugs - Definition, routes of drug excretion
- General mechanisms of drug action and factors modifying drug action
2. Drugs Acting on the Peripheral Nervous System
- Steps involved in neurohumoral transmission
- Definition, classification, pharmacological actions, dose, indications, and contraindications of
a) Cholinergic drugs
b) Anti-Cholinergic drugs
c) Adrenergic drugs
d) Anti-adrenergic drugs
e) Neuromuscular blocking agents
f) Drugs used in Myasthenia gravis
g) Local anaesthetic agents
h) Non-Steroidal Anti-Inflammatory drugs (NSAIDs)
3. Drugs Acting on the Eye
- Definition, classification, pharmacological actions, dose, indications and contraindications of
- Miotics
- Mydriatics
- Drugs used in Glaucoma
4. Drugs Acting on the Central Nervous System
Definition, classification, pharmacological actions, dose, indications, and contraindications of
- General anaesthetics
- Hypnotics and sedatives
- Anti-Convulsant drugs
- Anti-anxiety drugs
- Anti-depressant drugs
- Anti-psychotics
- Nootropic agents
- Centrally acting muscle relaxants
- Opioid analgesics
5. Drugs Acting on the Cardiovascular System
Definition, classification, pharmacological actions, dose, indications, and contraindications of
- Anti-hypertensive drugs
- Anti-anginal drugs
- Anti-arrhythmic drugs
- Drugs used in atherosclerosis and
- Congestive heart failure
- Drug therapy for shock
6. Drugs Acting on Blood and Blood Forming Organs: Definition, classification, pharmacological actions, dose, indications, and contraindications of
- Hematinic agents
- Anti-coagulants
- Anti-platelet agents
- Thrombolytic drugs
7. Drugs Acting on the Respiratory System
Definition, classification, pharmacological actions, dose, indications, and contraindications of
- Bronchodilators
- Expectorants
- Anti-tussive agents
- Mucolytic agents
8. Drugs Acting on the Gastro Intestinal Tract
Definition, classification, pharmacological actions, dose, indications, and contraindications of
- Anti-ulcer drugs
- Anti-emetics
- Laxatives and purgatives
- Anti-diarrheal drugs
9. Drugs Acting on the Kidney
Definition, classification, pharmacological actions, dose, indications, and contraindications of
10. Hormones and Hormone Antagonists
Physiological and pathological role and clinical uses of
- Thyroid hormones
- Anti-thyroid drugs
- Parathormone
- Calcitonin
- Vitamin D
- Insulin
- Oral hypoglycemic agents
- Estrogen
- Progesterone
- Oxytocin
- Corticosteroids
11. Autocoids
- Physiological role of Histamine, 5 HT and Prostaglandins
- Classification, clinical uses, and adverse effects of antihistamines and 5 HT antagonists
12. Chemotherapeutic Agents:
Introduction, basic principles of chemotherapy of infections, infestations and neoplastic diseases, Classification, dose, indication and contraindications of drugs belonging to following classes:
- Penicillins
- Cephalosporins
- Aminoglycosides
- Fluoroquinolones
- Macrolides
- Tetracyclines
- Sulphonamides
- Anti-tubercular drugs
- Anti-fungal drugs
- Anti-viral drugs
- Anti-amoebic agents
- Anthelmintics
- Anti-malarial agents
- Anti-neoplastic agents
13. Biologicals
- Definition, types, and indications of biological agents with examples.
